/* DATA DESCRIPTION: Citation: Kötke, Danijela; Gandrass, Juergen; Xie, Zhiyong; Ebinghaus, Ralf (2021): Prioritised pharmaceuticals in German estuaries and coastal waters in 2015/2016 [dataset]. PANGAEA, https://doi.org/10.1594/PANGAEA.929500 Abstract: In this study a target analysis approach with method detection limits down to 0.01 ng L−1 was developed in order to determine ultra-trace pharmaceuticals in seawater of the German coast and their estuaries. The selection of target analytes based on a prioritisation commissioned by the German Environmental Agency considering occurrence in German surface waters, production volumes and ecotoxicological data. Using ultra-high pressure liquid chromatography coupled to a triple quadrupole mass spectrometer equipped with an electrospray ionisation source 21 prioritised pharmaceuticals out of seven therapeutical classes (antibiotics, iodinated X-ray contrast media (ICM), analgesics, lipid reducers, antiepileptics, anticonvulsants, beta-blockers) have been detected in the low to medium ng L−1-range. The most frequently measured substance groups in the German Baltic Sea and German Bight are the ICM, represented by the non-ionic ICM iomeprol (German Bightmax: 207 ng L−1; Baltic Seamax: 34.5 ng L−1) and the ionic ICM amidotrizoic acid (German Bight: 86.9 ng L−1), respectively. The same pattern of substance distribution could be detected in the German Bight, the German Baltic Sea and their inflows with lower concentrations in the offshore region that are partly a result of dilution with marine water. Pharmaceuticals entering the estuaries and coastal regions are an environmental issue since data on the ecotoxicological effects on aquatic marine organisms is limited. Especially the antibiotics clarithromycin and sulfamethoxazole could be ecotoxicologically/environmentally critical. Related to: Kötke, Danijela; Gandrass, Juergen; Xie, Zhiyong; Ebinghaus, Ralf (2019): Prioritised pharmaceuticals in German estuaries and coastal waters: Occurrence and environmental risk assessment. Environmental Pollution, 255, 113161, https://doi.org/10.1016/j.envpol.2019.113161 Project(s): Helmholtz-Zentrum Geesthacht, Institute of Coastal Research (HZG) (URI: https://www.hereon.de/) Coverage: MEDIAN LATITUDE: 54.066199 * MEDIAN LONGITUDE: 11.016778 * SOUTH-BOUND LATITUDE: 53.036000 * WEST-BOUND LONGITUDE: 8.078000 * NORTH-BOUND LATITUDE: 54.823000 * EAST-BOUND LONGITUDE: 14.535000 DATE/TIME START: 2015-05-29T12:00:00 * DATE/TIME END: 2016-03-16T16:40:00 MINIMUM DEPTH, water: 0 m * MAXIMUM DEPTH, water: 0 m Event(s): LP20150529_Stat_E1 * LATITUDE: 53.843000 * LONGITUDE: 8.941000 * DATE/TIME: 2015-06-02T11:40:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_E2 * LATITUDE: 53.874000 * LONGITUDE: 9.238000 * DATE/TIME: 2015-06-02T12:35:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_E3 * LATITUDE: 53.745000 * LONGITUDE: 9.407000 * DATE/TIME: 2015-06-02T13:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_E4 * LATITUDE: 53.605000 * LONGITUDE: 9.576000 * DATE/TIME: 2015-06-02T14:32:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_E5 * LATITUDE: 53.550000 * LONGITUDE: 9.819000 * DATE/TIME: 2015-06-02T15:31:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_GB1 * LATITUDE: 53.901000 * LONGITUDE: 8.686000 * DATE/TIME: 2015-05-29T12:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_GB2 * LATITUDE: 53.964000 * LONGITUDE: 8.522000 * DATE/TIME: 2015-05-29T12:45:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_GB3 * LATITUDE: 53.903000 * LONGITUDE: 8.078000 * DATE/TIME: 2015-05-29T14:48:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_GB4 * LATITUDE: 53.754000 * LONGITUDE: 8.189000 * DATE/TIME: 2015-05-29T16:20:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_GB5 * LATITUDE: 53.663000 * LONGITUDE: 8.380000 * DATE/TIME: 2015-05-29T17:25:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_W1 * LATITUDE: 53.459000 * LONGITUDE: 8.493000 * DATE/TIME: 2015-05-30T15:20:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_W2 * LATITUDE: 53.369000 * LONGITUDE: 8.501000 * DATE/TIME: 2015-05-30T14:50:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_W3 * LATITUDE: 53.279000 * LONGITUDE: 8.488000 * DATE/TIME: 2015-05-30T14:13:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) LP20150529_Stat_W4 * LATITUDE: 53.188000 * LONGITUDE: 8.537000 * DATE/TIME: 2015-05-30T13:17:00 * LOCATION: German Bight, North Sea * CAMPAIGN: LP20150529 * BASIS: Ludwig Prandtl * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS1 * LATITUDE: 53.976000 * LONGITUDE: 14.146000 * DATE/TIME: 2015-09-01T19:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS2 * LATITUDE: 54.060000 * LONGITUDE: 14.000000 * DATE/TIME: 2015-09-01T17:45:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS3 * LATITUDE: 54.348000 * LONGITUDE: 13.744000 * DATE/TIME: 2015-09-02T11:40:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS4 * LATITUDE: 54.404000 * LONGITUDE: 13.618000 * DATE/TIME: 2015-09-02T10:40:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS5 * LATITUDE: 54.318000 * LONGITUDE: 13.095000 * DATE/TIME: 2015-09-02T08:55:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS6 * LATITUDE: 54.455000 * LONGITUDE: 12.571000 * DATE/TIME: 2015-09-03T10:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS7 * LATITUDE: 54.353000 * LONGITUDE: 12.383000 * DATE/TIME: 2015-09-03T11:50:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS8 * LATITUDE: 54.181000 * LONGITUDE: 12.091000 * DATE/TIME: 2015-09-03T13:50:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS9 * LATITUDE: 54.156000 * LONGITUDE: 11.763000 * DATE/TIME: 2015-09-03T16:05:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS10 * LATITUDE: 53.992000 * LONGITUDE: 11.374000 * DATE/TIME: 2015-09-03T18:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS11 * LATITUDE: 53.948000 * LONGITUDE: 11.348000 * DATE/TIME: 2015-09-03T20:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS12 * LATITUDE: 53.941000 * LONGITUDE: 11.252000 * DATE/TIME: 2015-09-03T19:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS13 * LATITUDE: 53.970000 * LONGITUDE: 10.883000 * DATE/TIME: 2015-09-04T11:45:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS15 * LATITUDE: 54.141000 * LONGITUDE: 10.965000 * DATE/TIME: 2015-09-04T13:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS16 * LATITUDE: 54.356000 * LONGITUDE: 11.092000 * DATE/TIME: 2015-09-04T16:35:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS19 * LATITUDE: 54.427000 * LONGITUDE: 10.172000 * DATE/TIME: 2015-09-05T11:35:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS20 * LATITUDE: 54.462000 * LONGITUDE: 9.843000 * DATE/TIME: 2015-09-10T10:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS21 * LATITUDE: 54.660000 * LONGITUDE: 9.935000 * DATE/TIME: 2015-09-05T13:50:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_BS22 * LATITUDE: 54.823000 * LONGITUDE: 9.654000 * DATE/TIME: 2015-09-05T16:05:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_O1 * LATITUDE: 53.036000 * LONGITUDE: 14.312000 * DATE/TIME: 2015-08-23T09:06:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_O2 * LATITUDE: 53.383000 * LONGITUDE: 14.535000 * DATE/TIME: 2015-08-23T12:20:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_O3 * LATITUDE: 53.736000 * LONGITUDE: 14.174000 * DATE/TIME: 2015-08-23T14:55:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1508_Stat_P1 * LATITUDE: 53.860000 * LONGITUDE: 13.690000 * DATE/TIME: 2015-08-23T18:35:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1508 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS4 * LATITUDE: 54.403550 * LONGITUDE: 13.617940 * DATE/TIME: 2016-03-15T11:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS5 * LATITUDE: 54.318430 * LONGITUDE: 13.095270 * DATE/TIME: 2016-03-15T09:45:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS6 * LATITUDE: 54.455220 * LONGITUDE: 12.570570 * DATE/TIME: 2016-03-15T12:15:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS7 * LATITUDE: 54.352720 * LONGITUDE: 12.383140 * DATE/TIME: 2016-03-15T13:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS8 * LATITUDE: 54.180550 * LONGITUDE: 12.090590 * DATE/TIME: 2016-03-15T14:50:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS9 * LATITUDE: 54.155920 * LONGITUDE: 11.762790 * DATE/TIME: 2016-03-15T16:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS11 * LATITUDE: 53.948180 * LONGITUDE: 11.347780 * DATE/TIME: 2016-03-15T18:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS14 * LATITUDE: 54.001369 * LONGITUDE: 10.783602 * DATE/TIME: 2016-03-16T09:05:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS15 * LATITUDE: 54.141240 * LONGITUDE: 10.964680 * DATE/TIME: 2016-03-16T10:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS16 * LATITUDE: 54.355930 * LONGITUDE: 11.091590 * DATE/TIME: 2016-03-16T11:30:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS17 * LATITUDE: 54.324980 * LONGITUDE: 10.667040 * DATE/TIME: 2016-03-16T12:10:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS18 * LATITUDE: 54.415750 * LONGITUDE: 10.415420 * DATE/TIME: 2016-03-16T12:55:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS19 * LATITUDE: 54.427230 * LONGITUDE: 10.171640 * DATE/TIME: 2016-03-16T14:00:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS20 * LATITUDE: 54.461990 * LONGITUDE: 9.843390 * DATE/TIME: 2016-03-16T15:10:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS21 * LATITUDE: 54.659580 * LONGITUDE: 9.934510 * DATE/TIME: 2016-03-16T15:55:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) SB1603_Stat_BS22 * LATITUDE: 54.822900 * LONGITUDE: 9.654260 * DATE/TIME: 2016-03-16T16:40:00 * LOCATION: German Bight, North Sea * CAMPAIGN: SB1603 * METHOD/DEVICE: Water sample (WS) Comment: Date/Time = local time Temperature, water; Salinity and pH method:For campaigns SB1603 and SB1508: oxygen, conductivity, temperature, pH; Multimeter 3430 WTW. For campaign LP20150529: Measurement by on-line-in-situ FerryBox-System. Parameter(s): Event label (Event) * PI: Kötke, Danijela (danijela.koetke@hzg.de) Campaign of event (Campaign) * PI: Kötke, Danijela (danijela.koetke@hzg.de) Latitude of event (Latitude) * PI: Kötke, Danijela (danijela.koetke@hzg.de) Longitude of event (Longitude) * PI: Kötke, Danijela (danijela.koetke@hzg.de) Date/Time of event (Date/Time) * PI: Kötke, Danijela (danijela.koetke@hzg.de) DEPTH, water [m] (Depth water) * GEOCODE * PI: Kötke, Danijela (danijela.koetke@hzg.de) Temperature, water [°C] (Temp) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: See description in dataset comment * COMMENT: measured in water column Salinity (Sal) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: See description in dataset comment * COMMENT: measured in water column pH (pH) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: See description in dataset comment * COMMENT: measured in water column Nadolol [ng/l] (Nadolol) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: <0.01ng/l, limit of detection for LP20150529: <0.01ng/l, limit of quantification for SB1603 and SB1508: 0.01ng/l, limit of quantification for LP20150529: 0.03ng/l Paracetamol [ng/l] (Paracetamol) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.01ng/l, limit of detection for LP20150529: 0.14ng/l, limit of quantification for SB1603 and SB1508: 0.03ng/l, limit of quantification for LP20150529: 0.46ng/l Carbamazepine [ng/l] (Carbamazepine) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.11ng/l, limit of detection for LP20150529: 0.33ng/l, limit of quantification for SB1603 and SB1508: 0.38ng/l, limit of quantification for LP20150529: 1.12ng/l Diclofenac [ng/l] (Diclofenac) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.03ng/l, limit of detection for LP20150529: 0.18ng/l, limit of quantification for SB1603 and SB1508: 0.1ng/l, limit of quantification for LP20150529: 0.61ng/l Iohexol [ng/l] (Iohexol) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.17ng/l, limit of detection for LP20150529: 0.34ng/l, limit of quantification for SB1603 and SB1508: 0.26ng/l, limit of quantification for LP20150529: 0.53ng/l Iopromide [ng/l] (Iopromide) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.17ng/l, limit of detection for LP20150529: 0.3ng/l, limit of quantification for SB1603 and SB1508: 0.27ng/l, limit of quantification for LP20150529: 0.85ng/l Lincomycin [ng/l] (Lincomycin) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: <0.01ng/l, limit of detection for LP20150529: 0.01ng/l, limit of quantification for SB1603 and SB1508: 0.01ng/l, limit of quantification for LP20150529: 0.01ng/l Propranolol [ng/l] (Propranolol) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.02ng/l, limit of detection for LP20150529: 0.03ng/l, limit of quantification for SB1603 and SB1508: 0.07ng/l, limit of quantification for LP20150529: 0.09ng/l Sulfadimethoxine [ng/l] (Sulfadimethoxine) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.01ng/l, limit of detection for LP20150529: 0.01ng/l, limit of quantification for SB1603 and SB1508: 0.02ng/l, limit of quantification for LP20150529: 0.04ng/l Sulfamethoxazole [ng/l] (Sulfamethoxazole) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.01ng/l, limit of detection for LP20150529: 0.02ng/l, limit of quantification for SB1603 and SB1508: 0.02ng/l, limit of quantification for LP20150529: 0.07ng/l Bezafibrate [ng/l] (Bezafibrate) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.03ng/l, limit of detection for LP20150529: 0.06ng/l, limit of quantification for SB1603 and SB1508: 0.18ng/l, limit of quantification for LP20150529: 0.36ng/l Clarithromycin [ng/l] (Clarithromycin) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.01ng/l, limit of detection for LP20150529: 0.01ng/l, limit of quantification for SB1603 and SB1508: 0.02ng/l, limit of quantification for LP20150529: 0.03ng/l Erythromycin [ng/l] (Erythromycin) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: <0.01ng/l, limit of detection for LP20150529: <0.01ng/l, limit of quantification for SB1603 and SB1508: 0.01ng/l, limit of quantification for LP20150529: 0.01ng/l Iomeprol [ng/l] (Iomeprol) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.16ng/l, limit of detection for LP20150529: 0.99ng/l, limit of quantification for SB1603 and SB1508: 0.4ng/l, limit of quantification for LP20150529: 3.29ng/l Iopamidol [ng/l] (Iopamidol) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.15ng/l, limit of detection for LP20150529: 0.34ng/l, limit of quantification for SB1603 and SB1508: 0.34ng/l, limit of quantification for LP20150529: 0.53ng/l Primidone [ng/l] (Primidone) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.04ng/l, limit of detection for LP20150529: 0.1ng/l, limit of quantification for SB1603 and SB1508: 0.13ng/l, limit of quantification for LP20150529: 0.34ng/l Roxithromycin [ng/l] (Roxithromycin) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.01ng/l, limit of detection for LP20150529: 0.02ng/l, limit of quantification for SB1603 and SB1508: 0.04ng/l, limit of quantification for LP20150529: 0.06ng/l Sulfamethazine [ng/l] (Sulfamethazine) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.07ng/l, limit of detection for LP20150529: 0.33ng/l, limit of quantification for SB1603 and SB1508: 0.22ng/l, limit of quantification for LP20150529: 1.09ng/l Tiamulin [ng/l] (Tiamulin) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for SB1603 and SB1508: 0.01ng/l, limit of detection for LP20150529: <0.01ng/l, limit of quantification for SB1603 and SB1508: 0.02ng/l, limit of quantification for LP20150529: 0.02ng/l Amidotrizoic acid [ng/l] (Amidotrizoic acid) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for LP20150529: 0.05ng/l, limit of quantification for LP20150529: 0.35ng/l Ioxitalamic acid [ng/l] (Ioxitalamic acid) * PI: Kötke, Danijela (danijela.koetke@hzg.de) * METHOD/DEVICE: Solid-phase extraction (SPE) and cleanup, coupled liquid chromatography tandem mass spectrometry (LC-MS/MS) * COMMENT: measured in water column, limit of detection for LP20150529: 0.06ng/l, limit of quantification for LP20150529: 0.36ng/l License: Creative Commons Attribution 4.0 International (CC-BY-4.0) (URI: https://creativecommons.org/licenses/by/4.0/) Size: 1176 data points */ Event Campaign Latitude Longitude Date/Time Depth water [m] Temp [°C] Sal pH Nadolol [ng/l] Paracetamol [ng/l] Carbamazepine [ng/l] Diclofenac [ng/l] Iohexol [ng/l] Iopromide [ng/l] Lincomycin [ng/l] Propranolol [ng/l] Sulfadimethoxine [ng/l] Sulfamethoxazole [ng/l] Bezafibrate [ng/l] Clarithromycin [ng/l] Erythromycin [ng/l] Iomeprol [ng/l] Iopamidol [ng/l] Primidone [ng/l] Roxithromycin [ng/l] Sulfamethazine [ng/l] Tiamulin [ng/l] Amidotrizoic acid [ng/l] Ioxitalamic acid [ng/l] SB1603_Stat_BS5 SB1603 54.3184 13.0953 2016-03-15T09:45:00 0 4.3 7.6 8.5 <0.01 <0.01 8.96 0.70 2.04 3.34 0.02 0.07 0.06 2.96 0.53 0.42 0.14 34.50 3.11 6.71 0.48 <0.22 <0.02 SB1603_Stat_BS4 SB1603 54.4036 13.6179 2016-03-15T11:00:00 0 4.7 8.0 8.7 <0.01 <0.01 8.26 0.25 1.92 3.33 0.03 0.11 0.10 3.29 0.19 0.19 0.04 5.85 0.89 4.74 0.29 <0.22 0.07 SB1603_Stat_BS6 SB1603 54.4552 12.5706 2016-03-15T12:15:00 0 6.7 9.2 8.1 <0.01 <0.01 3.73 0.11 1.08 1.12 <0.01 0.13 0.10 1.93 <0.03 0.15 0.04 6.63 1.03 4.21 0.28 <0.22 0.21 SB1603_Stat_BS7 SB1603 54.3527 12.3831 2016-03-15T13:30:00 0 7.1 10.1 8.2 <0.01 <0.01 2.89 <0.10 0.67 0.87 <0.01 0.09 0.10 1.55 <0.03 0.08 0.04 3.35 0.66 4.56 0.19 <0.22 0.08 SB1603_Stat_BS8 SB1603 54.1805 12.0906 2016-03-15T14:50:00 0 6.1 10.2 8.2 <0.01 <0.01 3.42 0.51 1.99 1.14 <0.01 <0.07 0.10 1.64 <0.18 0.14 0.07 8.72 2.85 3.47 0.20 <0.07 <0.01 SB1603_Stat_BS9 SB1603 54.1559 11.7628 2016-03-15T16:30:00 0 5.9 9.4 8.3 <0.01 <0.01 2.88 <0.10 0.69 1.14 <0.01 0.09 0.11 1.68 <0.03 0.08 0.03 2.41 0.51 3.64 0.20 <0.22 0.10 SB1603_Stat_BS11 SB1603 53.9482 11.3478 2016-03-15T18:00:00 0 6.2 13.0 8.5 <0.01 <0.01 2.58 <0.10 1.63 0.62 <0.01 <0.02 0.09 1.62 <0.03 0.07 0.02 6.59 1.46 3.05 0.07 <0.22 <0.01 SB1603_Stat_BS14 SB1603 54.0014 10.7836 2016-03-16T09:05:00 0 4.7 11.5 8.5 <0.01 <0.01 2.95 0.19 1.27 0.93 <0.01 <0.02 0.09 1.53 <0.03 0.09 0.04 4.99 1.52 4.36 0.09 <0.22 <0.01 SB1603_Stat_BS15 SB1603 54.1412 10.9647 2016-03-16T10:00:00 0 5.1 10.8 8.3 <0.01 <0.01 2.82 0.18 0.83 1.05 <0.01 <0.02 0.09 1.78 <0.03 0.11 0.03 2.55 0.63 3.15 0.15 <0.22 <0.02 SB1603_Stat_BS16 SB1603 54.3559 11.0916 2016-03-16T11:30:00 0 5.9 9.0 8.3 <0.01 <0.01 2.57 <0.10 0.65 0.88 <0.01 <0.02 0.11 1.67 <0.03 0.04 0.04 1.78 0.55 3.74 0.04 <0.22 <0.01 SB1603_Stat_BS17 SB1603 54.3250 10.6670 2016-03-16T12:10:00 0 6.3 14.7 8.3 <0.01 <0.01 2.53 <0.10 0.97 0.78 <0.01 <0.02 0.08 1.36 <0.03 0.06 0.03 4.45 1.39 2.74 0.06 <0.22 <0.02 SB1603_Stat_BS18 SB1603 54.4158 10.4154 2016-03-16T12:55:00 0 6.4 18.3 8.3 <0.01 0.42 2.08 0.17 0.76 0.48 <0.01 <0.02 0.06 1.18 <0.03 0.08 0.04 5.34 2.04 2.37 0.11 <0.22 <0.02 SB1603_Stat_BS19 SB1603 54.4272 10.1716 2016-03-16T14:00:00 0 8.1 18.2 8.3 <0.01 0.57 2.73 0.84 1.20 0.52 0.02 <0.07 0.04 1.85 0.24 0.34 0.14 13.10 12.00 3.26 0.35 <0.22 <0.01 SB1603_Stat_BS20 SB1603 54.4620 9.8434 2016-03-16T15:10:00 0 8.8 16.1 8.2 <0.01 <0.01 1.98 0.47 0.86 0.42 <0.01 <0.02 0.06 1.36 <0.03 0.11 0.05 5.90 2.23 2.29 0.10 <0.22 <0.01 SB1603_Stat_BS21 SB1603 54.6596 9.9345 2016-03-16T15:55:00 0 7.0 10.2 8.5 <0.01 <0.01 9.20 3.47 2.70 0.64 0.28 0.09 0.07 4.18 0.99 1.22 0.15 66.50 14.60 7.08 0.47 0.87 0.05 SB1603_Stat_BS22 SB1603 54.8229 9.6543 2016-03-16T16:40:00 0 6.2 13.9 8.3 <0.01 <0.01 2.45 0.35 1.06 0.56 0.03 <0.02 0.08 1.59 0.64 0.16 0.12 4.82 6.59 3.22 0.21 <0.22 <0.01 LP20150529_Stat_E1 LP20150529 53.8430 8.9410 2015-06-02T11:40:00 0 14.3 7.5 8.1 <0.01 <0.14 69.70 6.03 12.30 68.50 0.17 0.25 0.32 39.20 0.40 0.23 0.37 215.00 19.40 6.87 0.16 2.30 0.03 116.00 1.53 LP20150529_Stat_E2 LP20150529 53.8740 9.2380 2015-06-02T12:35:00 0 14.8 2.7 8.0 <0.01 <0.14 57.60 4.78 10.30 53.90 0.22 0.25 0.25 31.50 0.37 0.75 0.52 177.00 17.50 22.70 0.06 1.31 0.07 91.90 1.10 LP20150529_Stat_E3 LP20150529 53.7450 9.4070 2015-06-02T13:30:00 0 15.1 0.8 7.9 <0.01 <0.14 82.60 10.80 17.40 87.80 0.29 0.24 0.24 42.50 0.55 0.13 0.21 302.00 25.70 26.90 <0.02 1.44 0.03 170.00 3.09 LP20150529_Stat_E4 LP20150529 53.6050 9.5760 2015-06-02T14:32:00 0 15.8 0.6 7.7 <0.01 <0.14 89.10 18.60 20.80 104.00 0.27 0.38 0.19 39.30 1.06 0.20 0.34 378.00 29.10 30.10 <0.02 1.38 0.04 165.00 3.30 LP20150529_Stat_E5 LP20150529 53.5500 9.8190 2015-06-02T15:31:00 0 16.4 0.5 7.6 <0.01 <0.14 105.50 24.40 10.40 124.00 0.26 0.47 0.14 31.80 2.33 0.57 1.01 242.00 12.80 49.10 0.09 1.74 0.07 61.50 0.91 LP20150529_Stat_GB1 LP20150529 53.9010 8.6860 2015-05-29T12:00:00 0 13.8 22.5 8.3 <0.03 <0.14 20.10 0.87 9.28 22.30 0.13 0.15 0.13 12.10 0.52 0.57 0.31 99.30 11.90 8.16 0.17 <1.09 0.10 33.80 0.65 LP20150529_Stat_GB2 LP20150529 53.9640 8.5220 2015-05-29T12:45:00 0 14.0 26.3 8.3 <0.03 <0.14 13.30 <0.61 6.35 15.80 0.10 <0.09 0.09 7.60 0.43 0.40 0.21 62.00 8.95 4.02 0.13 <0.33 0.05 LP20150529_Stat_GB3 LP20150529 53.9030 8.0780 2015-05-29T14:48:00 0 13.3 30.0 8.3 <0.03 <0.14 4.78 <0.61 0.98 7.27 0.07 <0.09 0.04 1.78 <0.36 0.41 0.13 7.66 0.85 1.90 0.09 <1.09 0.02 1.71 <0.36 LP20150529_Stat_GB4 LP20150529 53.7540 8.1890 2015-05-29T16:20:00 0 14.1 26.8 8.2 <0.14 12.40 0.11 31.80 1.20 LP20150529_Stat_GB5 LP20150529 53.6630 8.3800 2015-05-29T17:25:00 0 14.5 18.5 8.1 <0.03 <0.14 29.70 4.82 25.50 34.10 0.16 0.22 0.13 13.00 2.06 1.66 0.94 207.00 31.60 9.73 0.38 <1.09 0.05 86.90 2.35 LP20150529_Stat_W1 LP20150529 53.4590 8.4930 2015-05-30T15:20:00 0 15.2 6.8 7.9 <0.01 <0.14 65.70 14.10 28.90 65.20 0.29 0.38 0.31 24.80 3.44 1.71 1.59 325.00 41.40 18.60 0.37 <1.09 0.06 177.00 3.23 LP20150529_Stat_W2 LP20150529 53.3690 8.5010 2015-05-30T14:50:00 0 15.6 2.2 7.9 <0.01 <0.14 87.60 23.40 39.00 90.20 0.44 0.50 0.47 32.30 4.71 1.47 2.00 484.00 59.50 28.80 0.45 <1.09 0.05 221.00 3.79 LP20150529_Stat_W3 LP20150529 53.2790 8.4880 2015-05-30T14:13:00 0 16.1 0.8 8.0 <0.01 <0.14 88.90 23.50 39.20 87.40 0.47 0.58 0.49 32.70 5.03 2.84 2.87 488.00 60.50 25.90 0.88 <0.33 0.05 207.00 3.51 LP20150529_Stat_W4 LP20150529 53.1880 8.5370 2015-05-30T13:17:00 0 16.6 0.8 8.0 <0.03 <0.14 92.60 27.10 38.10 96.90 0.41 0.70 0.34 35.10 6.02 8.07 3.90 463.00 59.80 29.00 2.86 <1.09 0.08 222.00 4.11 SB1508_Stat_O1 SB1508 53.0360 14.3120 2015-08-23T09:06:00 0 22.6 0.4 8.4 0.01 <0.01 162.00 2.29 10.10 94.50 0.54 0.08 0.06 20.30 <0.03 1.54 0.29 21.10 0.73 15.30 0.16 0.97 0.08 SB1508_Stat_O2 SB1508 53.3830 14.5350 2015-08-23T12:20:00 0 25.6 0.4 7.9 <0.01 <0.01 149.00 1.59 7.91 55.40 0.46 0.10 0.06 15.40 <0.03 1.69 0.32 23.70 0.98 19.80 0.23 0.45 0.11 SB1508_Stat_O3 SB1508 53.7360 14.1740 2015-08-23T14:55:00 0 24.4 1.9 8.7 <0.01 <0.01 74.20 <0.03 6.27 30.00 0.09 <0.02 <0.01 5.47 <0.03 1.05 0.17 21.10 <0.34 8.31 0.10 <0.22 0.03 SB1508_Stat_P1 SB1508 53.8600 13.6900 2015-08-23T18:35:00 0 22.4 0.3 7.9 <0.01 <0.01 82.00 1.02 0.29 21.00 0.07 0.20 <0.01 3.35 <0.03 0.96 0.58 251.00 2.97 24.70 3.64 <0.22 0.02 SB1508_Stat_BS1 SB1508 53.9760 14.1460 2015-09-01T19:00:00 0 20.9 7.6 8.2 <0.01 <0.01 6.94 <0.03 0.58 2.37 0.02 <0.02 0.08 1.52 <0.03 0.12 <0.01 1.83 <0.15 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS2 SB1508 54.0600 14.0000 2015-09-01T17:45:00 0 21.2 7.6 8.3 <0.01 <0.01 6.49 0.29 0.47 1.97 0.02 <0.02 0.07 1.50 <0.03 0.12 0.09 1.47 <0.15 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS3 SB1508 54.3480 13.7440 2015-09-02T11:40:00 0 19.2 7.8 8.3 <0.01 <0.01 6.51 <0.03 0.49 2.01 0.02 <0.02 0.08 1.49 <0.03 0.08 <0.01 1.97 <0.15 <0.04 <0.04 <0.07 <0.02 SB1508_Stat_BS4 SB1508 54.4040 13.6180 2015-09-02T10:40:00 0 18.6 7.9 8.3 <0.01 <0.01 6.91 <0.03 0.60 2.13 0.02 <0.02 0.06 1.57 <0.03 0.08 <0.01 2.51 <0.15 <0.04 <0.04 <0.07 <0.02 SB1508_Stat_BS5 SB1508 54.3180 13.0950 2015-09-02T08:55:00 0 18.2 8.2 8.2 <0.01 <0.01 10.60 0.50 0.36 1.47 0.01 <0.07 0.04 1.52 <0.03 0.20 0.09 9.82 <0.15 <0.04 0.07 <0.07 <0.01 SB1508_Stat_BS6 SB1508 54.4550 12.5710 2015-09-03T10:30:00 0 18.0 8.9 8.2 <0.01 <0.01 3.48 <0.03 0.29 1.06 0.01 <0.02 0.09 1.14 <0.03 0.05 <0.01 1.05 <0.15 <0.04 <0.01 <0.07 <0.01 SB1508_Stat_BS7 SB1508 54.3530 12.3830 2015-09-03T11:50:00 0 17.5 9.1 8.2 <0.01 <0.01 3.11 <0.03 0.32 0.99 0.01 <0.02 0.09 1.10 <0.03 0.04 <0.01 1.19 <0.15 <0.04 <0.01 <0.07 <0.01 SB1508_Stat_BS8 SB1508 54.1810 12.0910 2015-09-03T13:50:00 0 17.6 9.8 8.1 <0.01 <0.01 5.93 <0.03 0.64 1.65 0.01 <0.07 0.08 1.59 <0.03 0.07 <0.01 4.31 <0.34 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS9 SB1508 54.1560 11.7630 2015-09-03T16:05:00 0 18.3 9.6 8.2 <0.01 <0.01 3.01 <0.03 0.28 1.17 0.01 <0.02 0.08 1.10 <0.03 0.03 <0.01 1.26 <0.15 <0.04 <0.01 <0.07 <0.01 SB1508_Stat_BS10 SB1508 53.9920 11.3740 2015-09-03T18:00:00 0 18.5 11.2 8.3 <0.01 <0.01 3.72 <0.03 0.33 0.47 0.02 <0.02 0.06 0.93 <0.03 0.05 0.02 2.37 <0.15 <0.04 <0.01 <0.07 <0.01 SB1508_Stat_BS11 SB1508 53.9480 11.3480 2015-09-03T20:00:00 0 18.4 11.5 8.2 <0.01 <0.01 4.34 <0.03 <0.26 0.52 0.02 <0.02 0.06 0.90 <0.03 0.11 <0.01 2.64 <0.15 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS12 SB1508 53.9410 11.2520 2015-09-03T19:30:00 0 18.7 11.6 8.3 <0.01 <0.01 3.48 <0.03 <0.26 0.54 0.04 <0.02 0.06 0.99 <0.03 0.05 <0.01 2.21 <0.15 <0.04 <0.01 <0.07 <0.01 SB1508_Stat_BS13 SB1508 53.9700 10.8830 2015-09-04T11:45:00 0 16.9 11.6 8.2 <0.01 <0.01 6.24 <0.03 1.70 0.66 0.02 <0.02 0.07 1.95 <0.03 0.11 0.09 17.80 0.84 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS15 SB1508 54.1410 10.9650 2015-09-04T13:30:00 0 17.2 11.0 8.3 <0.01 <0.01 3.31 <0.03 0.48 0.72 0.01 <0.02 0.08 1.09 <0.03 0.04 0.04 3.52 <0.15 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS16 SB1508 54.3560 11.0920 2015-09-04T16:35:00 0 17.5 12.5 8.2 <0.01 <0.01 3.82 <0.03 0.32 0.73 0.01 <0.02 0.07 0.96 <0.03 0.04 0.03 1.70 <0.15 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS19 SB1508 54.4270 10.1720 2015-09-05T11:35:00 0 17.3 14.9 8.1 <0.01 <0.01 3.51 <0.03 0.38 0.76 0.01 <0.02 0.05 1.22 <0.03 0.06 0.05 4.60 0.55 <0.04 <0.04 <0.07 <0.01 SB1508_Stat_BS20 SB1508 54.4620 9.8430 2015-09-10T10:30:00 0 16.9 14.3 8.2 <0.01 <0.01 3.51 <0.03 0.37 0.85 0.01 <0.02 0.06 1.13 <0.03 0.04 0.03 2.47 <0.15 <0.04 <0.01 <0.07 <0.01 SB1508_Stat_BS21 SB1508 54.6600 9.9350 2015-09-05T13:50:00 0 16.5 11.2 8.5 <0.01 <0.01 16.50 0.48 1.66 1.39 0.10 <0.02 <0.01 1.53 <0.03 0.20 0.09 123.00 0.66 <0.04 <0.04 <0.22 <0.01 SB1508_Stat_BS22 SB1508 54.8230 9.6540 2015-09-05T16:05:00 0 16.9 14.9 8.5 <0.01 <0.01 3.97 <0.10 0.55 0.55 0.01 <0.02 0.04 0.74 0.48 0.07 0.05 6.61 <0.15 <0.04 <0.04 <0.07 <0.01