/* DATA DESCRIPTION:
Citation:	Falfushynska, Halina; Sokolov, Eugene P; Haider, Fouzia; Oppermann, Christina; Kragl, Udo; Ruth, Wolfgang; Stock, Marius; Glufke, Sabrina; Winkel, Eileen J; Sokolova, Inna M (2019): Effect of atorvastatin on the xenobioitic detoxification of blue mussels, Mytilus edulis [dataset]. PANGAEA, https://doi.org/10.1594/PANGAEA.898930
Abstract:	Increasing concentration of biologically active pharmaceutical compounds can affect marine organisms. The bioavailability and environmental stability of these compounds make them potential threat to these organisms, specially the sessile organisms. We have examined the effects of atorvastatin, a globally prescribed drug, on the blue mussels – Mytilus edulis. In this data set, we presents the effect of atorvastatin (ATO) on detoxification of Mytilus edulis.
Keyword(s):	Atorvastatin; Mytilus edulis; PgP
Related to:	Falfushynska, Halina; Sokolov, Eugene P; Haider, Fouzia; Oppermann, Christina; Kragl, Udo; Ruth, Wolfgang; Stock, Marius; Glufke, Sabrina; Winkel, Eileen J; Sokolova, Inna M (2019): Effects of a common pharmaceutical, atorvastatin, on energy metabolism and detoxification mechanisms of a marine bivalve Mytilus edulis. Aquatic Toxicology, 208, 47-61, https://doi.org/10.1016/j.aquatox.2018.12.022
Parameter(s):	Species (Species) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de)
	Treatment (Treat) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de) * COMMENT: Exposure to Atorvastatin
	Time in weeks [weeks] (Time weeks) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de) * COMMENT: Exposure time
	Sample ID (Sample ID) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de)
	Mytilus edulis, mass [g] (M. edulis m) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de) * COMMENT: Total body mass
	Rhodamine B efflux rate [nmol/h/g] (RB efflux rate) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de)
	P-glycoprotein activity [nmol/h/g] (PgP activity) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de)
	Comment (Comment) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de) * COMMENT: PgP activity
	Diffusion efflux rate [nmol/h/g] (Diff efflux rate) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de)
	Comment (Comment) * PI: Sokolova, Inna M (https://orcid.org/0000-0002-2068-4302, inna.sokolova@uni-rostock.de) * COMMENT: Outlier
License:	Creative Commons Attribution 4.0 International (CC-BY-4.0) (URI: https://creativecommons.org/licenses/by/4.0/)
Size:	143 data points
*/
Species	Treat (Exposure to Atorvastatin)	Time weeks [weeks] (Exposure time)	Sample ID	M. edulis m [g] (Total body mass)	RB efflux rate [nmol/h/g]	PgP activity [nmol/h/g]	Comment (PgP activity)	Diff efflux rate [nmol/h/g]	Comment (Outlier)
M. edulis	Control	0	C1-A	0.893	8.614	0.000	activity below detection limit	11.160	Outlier
M. edulis	Control	0	C1-B	1.275	11.228	4.127		7.101	
M. edulis	Control	0	C1-C	0.961	0.468	0.175		0.293	
M. edulis	Control	0	C1-D	1.369	14.226	5.224		9.002	
M. edulis	Control	0	C1-E	1.073	7.476	0.000	activity below detection limit	8.902	Outlier
M. edulis	Control	0	C2-A	1.648	21.732	13.008		8.723	
M. edulis	Control	0	C2-B	1.284	14.696	7.650		7.047	
M. edulis	Control	0	C2-C	1.370	7.034	5.242		1.791	
M. edulis	Control	0	C2-D	1.453	7.668	0.000	activity below detection limit	9.295	Outlier
M. edulis	Control	0	C2-E	0.982	20.829	13.809		7.020	
M. edulis	Exposed	4	AS1-A	1.675	4.245	0.100		4.144	Outlier
M. edulis	Exposed	4	AS1-B	1.599	3.685	1.700		1.985	
M. edulis	Exposed	4	AS1-C	1.369	3.050	1.192		1.858	
M. edulis	Exposed	4	AS1-D	1.268	4.022	2.650		1.372	
M. edulis	Exposed	4	AS1-E	0.949	4.761	2.415		2.346	
M. edulis	Exposed	4	AS2-A	1.262	1.678	0.837		0.837	
M. edulis	Exposed	4	AS2-B	1.052	3.844	2.082		2.082