Citation:

PANGAEA.898928

Name: Effect of atorvastatin on the membrane properties of blue mussels, Mytilus edulis
Published: 2019-03-04
License: https://creativecommons.org/licenses/by/4.0/
Keywords: Atorvastatin; GST; Mytilus edulis

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Published: 2019-03-04 • DOI registered: 2019-04-12

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Abstract:

Increasing concentration of biologically active pharmaceutical compounds can affect marine organisms. The bioavailability and environmental stability of these compounds make them potential threat to these organisms, specially the sessile organisms. We have examined the effects of atorvastatin, a globally prescribed drug, on the blue mussels – Mytilus edulis. In this data set, we presents the effect of atorvastatin (ATO) on the membrane properties of Mytilus edulis.

Keyword(s):

Atorvastatin; GST; Mytilus edulis

Related to:

Falfushynska, Halina; Sokolov, Eugene P; Haider, Fouzia; Oppermann, Christina; Kragl, Udo; Ruth, Wolfgang; Stock, Marius; Glufke, Sabrina; Winkel, Eileen J; Sokolova, Inna M (2019): Effects of a common pharmaceutical, atorvastatin, on energy metabolism and detoxification mechanisms of a marine bivalve Mytilus edulis. Aquatic Toxicology, 208, 47-61, https://doi.org/10.1016/j.aquatox.2018.12.022

Parameter(s):

#	Name	Short Name	Unit	Principal Investigator	Comment
1	Species	Species		Sokolova, Inna M
2	Treatment	Treat		Sokolova, Inna M	Exposure to Atorvastatin
3	Time in weeks	Time weeks	weeks	Sokolova, Inna M	Exposure time
4	Tissues	Tissues		Sokolova, Inna M
5	Sample ID	Sample ID		Sokolova, Inna M
6	NADPH-P450 reductase, activity per protein mass	NADPH-P450 reductase/protein	U/g	Sokolova, Inna M
7	7-ethoxyresorufin-O-deethylase, activity per protein mass	EROD/prot	U/g	Sokolova, Inna M
8	Glutathione S-transferase, activity per tissue mass	GST/tissue	U/g	Sokolova, Inna M	per wet tissue mass

License:

Creative Commons Attribution 4.0 International (CC-BY-4.0)

Size:

199 data points

Data

Download dataset as tab-delimited text — use the following character encoding:

1 Species	2 Treat	3 Time weeks [weeks]	4 Tissues	5 Sample ID	6 NADPH-P450 reductase/protein [U/g]	7 EROD/prot [U/g]	8 GST/tissue [U/g]
M. edulis	Control	0	Digestive gland	C2	164.074	0.382	44.668
M. edulis	Control	0	Digestive gland	C3	202.459	0.328	78.616
M. edulis	Control	0	Digestive gland	C4	153.910	0.240	23.228
M. edulis	Control	0	Digestive gland	C5	228.344	0.281	85.763
M. edulis	Control	0	Digestive gland	C1		0.248	75.043
M. edulis	Control	0	Digestive gland	C6	155.917	0.278	44.668
M. edulis	Control	0	Digestive gland	C7	202.207	0.294	32.161
M. edulis	Exposed	4	Digestive gland	A1	202.208	0.233	32.161
M. edulis	Exposed	4	Digestive gland	A2	340.748	0.187	23.228
M. edulis	Exposed	4	Digestive gland	A3	249.001	0.239	16.081
M. edulis	Exposed	4	Digestive gland	A4	147.277	0.123	50.029
M. edulis	Exposed	4	Digestive gland	A5	176.224	0.317	23.228
M. edulis	Exposed	4	Digestive gland	A6	238.481	0.282	30.374
M. edulis	Control	0	Gills	C1	1031.009	0.150	17.867
M. edulis	Control	0	Gills	C2	1521.529	0.113	14.294
M. edulis	Control	0	Gills	C3	1215.099	0.127	14.294
M. edulis	Control	0	Gills	C4	1596.956	0.065	8.934
M. edulis	Control	0	Gills	C5	1503.893	0.166	21.441
M. edulis	Control	0	Gills	C6	1211.697	0.064	10.720
M. edulis	Exposed	4	Gills	A1	1274.545	0.121	35.735
M. edulis	Exposed	4	Gills	A2	1431.673	0.115	35.735
M. edulis	Exposed	4	Gills	A3	1009.839	0.098	37.521
M. edulis	Exposed	4	Gills	A4	917.764	0.138	42.882
M. edulis	Exposed	4	Gills	A5	1451.262	0.121	55.389
M. edulis	Exposed	4	Gills	A6	1334.706	0.142	26.801