Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 Quintard Benoît Sicks Florian Dehnhard Martin Greenwood Alex D Franz Mathias 2018 Fecal glucocorticoid metabolites in captive Grévys zebras, and acute shedding of equine Herpesvirus dataset https://doi.org/10.1594/PANGAEA.888893 2018-04-23T09:53:19 Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 Quintard Benoît Sicks Florian Dehnhard Martin Greenwood Alex D Franz Mathias 2018 Environmental stressors may cause equine herpesvirus reactivation in captive Grévy's zebras (Equus grevyi) journal article PeerJ 6 https://doi.org/10.7717/peerj.5422 e5422 Equine Herpesviruses (EHV) are highly prevalent and often latent pathogens of equids which can be fatal when transmitted to non-equids. Stress and elevated glucocorticoids have been associated with EHV reactivation in domestic horses, but little is known about the correlation of stress and viral reactivation in wild equids. We investigated the effect of environmental stressors (long-distance transport and social group restructuring) on EHV reactivation in captive Grévys zebras. One mare was translocated by road transport from Zoo Mulhouse, France, to join a resident group of three mares in Tierpark Berlin, Germany. We measured fecal glucocorticoid metabolite (fGCM) concentrations daily in each individual from 6 days before the translocation event, to 14 days after translocation. EHV shedding was screened for all animals at Tierpark Berlin using an indirect sampling method. Following the translocation event we found significantly elevated fGCM concentrations in all animals compared to fGCM levels before the translocation event, which coincided with increased rates of EHV shedding. Our results support the hypothesis that environmental stressors induce viral reactivation in wild equids. This finding suggests that potentials stressors such as translocation and group restructuring should be considered in the management of zoological collections to reduce the risk of fatal EHV infections in novel hosts. Moreover, environmental stressors may also play an important role regarding EHV reactivation and spreading in wild equid populations. 13.5325 13.5325 52.5003 52.5003 13.5325 52.5003 not specified Tierpark_Berlin 52.5003 13.5325 Berlin, Germany Biology BIO 489 CC-BY-NC-3.0 Creative Commons Attribution-NonCommercial 3.0 Unported https://creativecommons.org/licenses/by-nc/3.0/ Day of study DOS day day Time T http://dbpedia.org/resource/Time Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 DOS [day] Phase Phase phase http://purl.obolibrary.org/obo/PATO_0000083 Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 a = before translocation, b = separation phase 1, c = common enclosure, d = separation phase 2 Phase (a = before translocation, b =...) Name Name Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 of individual, fr = Franzi, ki = Kianga, za = Zavadi, ek = Ekwe Name (of individual, fr = Franzi, k...) Status Status Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 residency: 1 = resident, 2 = translocated Status (residency: 1 = resident, 2 = ...) Status Status Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 EHV: 0 = non EHV shedding, 1 = EHV shedding Status (EHV: 0 = non EHV shedding, 1 ...) Fecal glucocorticoid metabolite fGCM ng/g Seeber Peter A seeber.pa@gmail.com 0000-0003-4401-8248 wet weight fGCM [ng/g] (wet weight) supplement citable author64948 author64949 author64950 author64951 author64952 author64953 event2882382 geocode1600 geocode1601 journal16720 license104 method10661 param121202 param153124 param163024 param7369 param79845 pi64948 ref95486 term1074108 term26632 term43975 term48982 topotype1