Gebbink, Wouter A; Sonne, Christian; Dietz, Rune; Kirkegaard, Maja; Born, Erik W; Muir, Derek C G; Letcher, Robert J (2008): (Table 1) Concentrations of neutral and phenolic organohalogen compounds in adipose tissue, blood, brain and liver of polar bears (Ursus maritimus) from East Greenland [dataset]. PANGAEA, https://doi.org/10.1594/PANGAEA.810194, Supplement to: Gebbink, WA et al. (2008): Target tissue selectivity and burdens of diverse classes of brominated and chlorinated contaminants in polar bears (Ursus maritimus) from East Greenland. Environmental Science & Technology, 42(3), 752-759, https://doi.org/10.1021/es071941f
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Abstract:
The tissue-specific composition of sum classes of brominated and chlorinated contaminants and metabolic/degradation byproducts was determined in adult male and female polar bears from East Greenland. Significantly (p < 0.05) higher concentrations of SUM-PCBs, various other organochlorines such as SUM-CHL, p,p'-DDE, SUM-CBz, SUM-HCHs, octachlorostyrene (OCS),SUM-mirex, dieldrin, the flame retardants SUM-PBDEs, and total-(R)-hexabromocyclododecane (HBCD), SUM-methylsulfonyl (MeSO2)-PCBs and 3-MeSO2-p,p'-DDE, were found in the adipose and liver tissues relative to whole blood and brain. In contrast, SUM-hydroxyl (OH)-PCB, 4-OH-heptachlorostyrene and SUM-OH-PBDE concentrations were significantly highest (p < 0.05) in whole blood, whereas the highest concentrations of SUM-OH-PBBs were found in the adipose tissue. Based on the total concentrations of all organohalogens in all three tissues and blood, the combined body burden was estimated to be 1.34 ± 0.12 g, where >91% of this amount was accounted for by the adipose tissue alone, followed by the liver, whole blood, and brain. These results show that factors such as protein association and lipid solubility appear to be differentially influencing the toxicokinetics, in terms of tissue composition/localization and burden, of organohalogen classes with respect to chemical structure and properties such as the type of halogenation (e.g., chlorination or bromination), and the presence or absence of additional phenyl group substituents (e.g., MeO and OH groups). The tissue- and blood-specific accumulation (or retention) among organohalogen classes indicates that exposure and any potential contaminant-mediated effects in these polar bears are likely tissue or blood specific.
Related to:
Gebbink, Wouter A; Sonne, Christian; Dietz, Rune; Kirkegaard, Maja; Rigét, Frank F; Born, Erik W; Muir, Derek C G; Letcher, Robert J (2008): Tissue-specific congener composition of organohalogen and metabolite contaminants in East Greenland polar bears (Ursus maritimus). Environmental Pollution, 152(3), 621-629, https://doi.org/10.1016/j.envpol.2007.07.001
Project(s):
Coverage:
Latitude: 74.000000 * Longitude: -20.000000
Comment:
Sample number is n = 20, unless otherwise indicated.
Sum-PCB = CB-28/31,-42,-44,-49,-52,-60,-64/71,-66/95,-70,-74,-84/101,-87,-97,-99,-105,-110,-118,-128,-129/178,-138,-141,-146,-149,-151,-153,-156/171/202,-158,-170/190,-172,-174,-177,-179,-180,-182/187,-183,-194,-195,-196/203,-200,-201,and-206
Sum-MeSO2-PCB: 3'/4'-MeSO2-CB49,3/4-MeSO2-CB52,3/4-MeSO2-CB64,3/4-MeSO2-CB70,3'/4'-MeSO2-CB87,3/4-MeSO2-CB91,3'/4'-MeSO2-CB101,3/4-MeSO2-CB110,3'/4'-MeSO2-CB132,3'/4'-MeSO2-CB141,3/4-MeSO2-CB149,3/4-MeSO2-CB174
Sum-OH-PCB: 4'-OH-CB79,4-OH-CB97,4'-OH-CB101/4-OH-CB134,4-OH-CB107/4'-OH-CB108,2'-OH-CB114,3-OH-CB118,4'-OH-CB120,4'-OH-CB127,4'-OH-CB130,3'-OH-CB138,4-OH-CB146,4'-OH-CB159,4-OH-CB162,4-OH-CB163,4'-OH-CB172,4'-OH-CB177,4-OH-CB178,3'-OH-CB180,3'-OH-CB182,3'-OH-CB183,3'-OH-CB184,4-OH-CB187,4-OH-CB193,4'-OH-CB199,4'-OH-CB200,4'-OH-CB201,4'-OH-CB202,4,4'-diOH-CB202,3'-OH-CB203/4'-OH-CB198,4'-OH-CB208.
Sum-CHL: oxychlordane, frans-chlordane, c/s-chlordane, frans-nonachlor, c/s-nonachlor, heptachlor-epoxide.
Sum-CBz: PeCBz, HCB. h 2-HCH: a-, ß-, y-HCH.
Sum-PBDE: BDE-17,28,-47,-66,-85,-99,-100,-138,-153,-154,-183,-190,-209.
Sum-OH-PBDE: 6'-OH-BDE17, 6'-OH-BDE17, 6'-OH-BDE49, 2'-OH-BDE68, 6-OH-BDE47, 3-OH-BDE47, 5-OH-BDE47, 4'-OH-BDE49, 4-OH-BDE42, 6-OH-BDE90, 6-OH-BDE99, 2-OH-BDE123, 6-OH-BDE85, 6-OH-BDE137.
Sum-OH-PBB: one tribrominated and two tetra-brominated OH-PBB.
Sum-MeO-PBDE: 4'-MeO-BDE17, 6'-MeO-BDE17, 2'-MeO-BDE28, 4-MeO-BDE42, 3-MeO-BDE47, 5-MeO-BDE47, 6-MeO-BDE47, 4'-MeO-BDE49, 6'-MeO-BDE49, 2'-MeO-BDE68, 6-MeO-BDE85, 6-MeO-BDE90, 6-MeO-BDE99, 2-MeO-BDE123, 6-MeO-BDE137.
Data extracted in the frame of a joint ICSTI/PANGAEA IPY effort, see http://doi.pangaea.de/10.1594/PANGAEA.150150
Parameter(s):
| # | Name | Short Name | Unit | Principal Investigator | Method/Device | Comment |
|---|---|---|---|---|---|---|
| 1 | Sample type | Samp type | Gebbink, Wouter A | |||
| 2 | Lipids | Lipids | % | Gebbink, Wouter A | ||
| 3 | Lipids, standard deviation | Lipids std dev | ± | Gebbink, Wouter A | ||
| 4 | Polychlorinated biphenyl | PCB | µg/g | Gebbink, Wouter A | ||
| 5 | Polychlorinated biphenyl, standard deviation | PCB std dev | ± | Gebbink, Wouter A | ||
| 6 | Methyl sulfone polychlorinated biphenyl | MeSO2-PCB | ng/g | Gebbink, Wouter A | ||
| 7 | Methyl sulfone polychlorinated biphenyl, standard deviation | MeSO2-PCB std dev | ± | Gebbink, Wouter A | ||
| 8 | Hydroxy-polychlorinated biphenyl | OH-PCB | ng/g | Gebbink, Wouter A | ||
| 9 | Hydroxy-polychlorinated biphenyl, standard deviation | OH-PCB std dev | ± | Gebbink, Wouter A | ||
| 10 | Chlordane | CHL | ng/g | Gebbink, Wouter A | brain: n = 12 | |
| 11 | Chlordane, standard deviation | CHL std dev | ± | Gebbink, Wouter A | ||
| 12 | para,para-Dichlorodiphenyldichloroethylene | pp-DDE | µg/g | Gebbink, Wouter A | mean or range min; blood: n = 9, brain: n = 2 | |
| 13 | Dichlorodiphenyldichloroethylene, standard deviation | DDE std dev | ± | Gebbink, Wouter A | p,p-DDE | |
| 14 | para,para-Dichlorodiphenyldichloroethylene | pp-DDE | µg/g | Gebbink, Wouter A | range max | |
| 15 | 3-methylsulfonyl p,p-dichlorodiphenyl dichloroethylene | 3-MeSO2-pp-DDE | ng/g | Gebbink, Wouter A | adip. t. and blood: n = 18 | |
| 16 | Dichlorodiphenyldichloroethylene, standard deviation | DDE std dev | ± | Gebbink, Wouter A | 3-MeSO2-pp-DDE | |
| 17 | Chlorinated benzene | CBz | ng/g | Gebbink, Wouter A | brain: n = 12 | |
| 18 | Chlorinated benzene, standard deviation | CBz std dev | ± | Gebbink, Wouter A | ||
| 19 | Hexachlorocyclohexane | HCH | ng/g | Gebbink, Wouter A | mean or range min; blood: n = 9, brain: n = 6, liver: n = 19 | |
| 20 | Hexachlorocyclohexane, standard deviation | HCH std dev | ± | Gebbink, Wouter A | ||
| 21 | Hexachlorocyclohexane | HCH | ng/g | Gebbink, Wouter A | range max | |
| 22 | Octachlorostyrene | OCS | ng/g | Gebbink, Wouter A | mean or range min; blood: n = 5, liver: n = 19 | |
| 23 | Octachlorostyrene, standard deviation | OCS st dev | ± | Gebbink, Wouter A | ||
| 24 | Octachlorostyrene | OCS | ng/g | Gebbink, Wouter A | range max | |
| 25 | Mirex | Mirex | ng/g | Gebbink, Wouter A | mean or range min; mirex + photomirex; adip. t: n = 16, blood: n = 9 | |
| 26 | Mirex, standard deviation | Mirex std dev | ± | Gebbink, Wouter A | ||
| 27 | Mirex | Mirex | ng/g | Gebbink, Wouter A | range max | |
| 28 | Dieldrin | Dieldrin | ng/g | Gebbink, Wouter A | liver: n = 19 | |
| 29 | Dieldrin, standard deviation | Dieldrin std dev | ± | Gebbink, Wouter A | ||
| 30 | 4-hydroxy-heptachlorostyrene | 4-OH-HpCS | ng/g | Gebbink, Wouter A | ||
| 31 | 4-hydroxy-heptachlorostyrene, standard deviation | 4-OH-HpCS std dev | ± | Gebbink, Wouter A | ||
| 32 | Pentachlorophenol | PCP | ng/g | Gebbink, Wouter A | ||
| 33 | Pentachlorophenol, standard deviation | PCP std dev | ± | Gebbink, Wouter A | ||
| 34 | Polybrominated diphenyl ethers | PBDE | ng/g | Gebbink, Wouter A | brain: n = 18 | |
| 35 | Polybrominated diphenyl ethers, standard deviation | PBDE std dev | ± | Gebbink, Wouter A | ||
| 36 | alpha-Hexabromocyclododecane | a-HBCD | ng/g | Gebbink, Wouter A | n = 13 | |
| 37 | Hexabromocyclododecane, standard deviation | HBCD std dev | ± | Gebbink, Wouter A | ||
| 38 | Hydroxylated polybrominated diphenyl ethers | OH-PBDE | ng/g | Gebbink, Wouter A | adip. t: n = 13, blood: n = 19 | |
| 39 | Hydroxylated polybrominated diphenyl ethers, standard deviation | OH-PBDE std dev | ± | Gebbink, Wouter A | ||
| 40 | Hydroxylated polybrominated biphenyl | OH-PBB | ng/g | Gebbink, Wouter A | mean or range min; adip. t and brain: n = 14, blood: n = 9, liver: n = 11 | |
| 41 | Hydroxylated polybrominated biphenyl, standard deviation | OH-PBB std dev | ± | Gebbink, Wouter A | ||
| 42 | Hydroxylated polybrominated biphenyl | OH-PBB | ng/g | Gebbink, Wouter A | range max | |
| 43 | Methoxylated polybrominated diphenyl ethers | MeO-PBDE | ng/g | Gebbink, Wouter A | range min; adip. t: n = 8, blood: n = 7 | |
| 44 | Methoxylated polybrominated diphenyl ethers | MeO-PBDE | ng/g | Gebbink, Wouter A | range max |
License:
Creative Commons Attribution 3.0 Unported (CC-BY-3.0)
Size:
130 data points